Top Boutique Hotels in St. Louis (2026)

Best Boutique Hotels in St. Louis

This guide to the best luxury, boutique, and design-forward hotels in St. Louis is manually curated by our editorial team based on first-hand research, verified guest reviews, location analysis, and overall service quality. Each hotel is selected to meet high standards of comfort, authenticity, and guest experience.

The Last Hotel
Hotels
1501 Washington Avenue, Downtown St. Louis, Saint Louis, MO 63103, United States

In a prime location in Saint Louis, The Last Hotel provides air-conditioned rooms, a fitness center, free WiFi and a shared lounge. This 4-star hotel offers a 24-hour front desk and an ATM. Private parking is available on site. All guest rooms in the hotel are equipped with a flat-screen TV with cable channels. At The Last Hotel every room includes bed linen and towels. The accommodation has a sun terrace. Popular points of interest near The Last Hotel include Laclede's Landing, Edward Jones Dome and Old Courthouse. The nearest airport is St. Louis Lambert International Airport, 13 miles from the hotel.

Guest Reviews:

- "Lots of character Receptionist and valets all very pleasant Highly recommended" - "Very close to the Busch stadium" - "The staff were wonderful. Helpful and kind. We left the car with the valet parking and they brought the car immediately when we needed it. We recommend this hotel." - "Beautiful and clean room. All the staff was very nice and willing to help." - "Amazing staff, and rooms. Valet and front desk were full of life, and very helpful!"

St. Louis Pet Friendly Boutique Hotels

boutique hotels in St. Louis
8.1
1843 reviews
From $181

No family member gets left behind at The Last Hotel! This pet-friendly gem welcomes furry companions with open arms, offering practical amenities that make traveling with pets easy. Explore the beautiful surroundings with nearby walking trails, ensuring both you and your pet enjoy your stay. Relax knowing that your beloved animal is comfortable alongside you in a vibrant setting that caters to all guests.

St. Louis Boutique Hotels with Parking

boutique hotels in St. Louis
8.1
1843 reviews
From $181

At The Last Hotel, seamless arrival is a top priority. Benefit from convenient on-site private parking that ensures both security and easy transit during your stay. Whether you're exploring the vibrant local scene or heading to nearby landmarks, you’ll appreciate the hassle-free experience. With a dedicated 24-hour front desk ready to assist, every aspect of your visit is designed for efficiency and comfort.

St. Louis Boutique Hotels with Entertainment

boutique hotels in St. Louis
8.1
1843 reviews
From $181

Experience the vibrant nightlife of Saint Louis at this energetic hotspot! The Last Hotel is ideally located near Laclede's Landing and Edward Jones Dome, providing easy access to exciting activities and local attractions. Unwind by the pool or mingle in the shared lounge, where you can meet like-minded travelers. With a lively atmosphere and a blend of entertainment options, your stay promises unforgettable moments in the heart of the city.

St. Louis Family Friendly Boutique Hotels

boutique hotels in St. Louis
8.1
1843 reviews
From $181

The Last Hotel is an excellent choice for families seeking a safe and welcoming environment. Enjoy spacious, air-conditioned rooms equipped with all the essentials, ensuring a stress-free bonding experience. Kids will love the nearby attractions, while parents can relax knowing their family is secure. The hotel's convenient location makes it easy to explore family-friendly destinations in Saint Louis, creating cherished memories together.

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